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The antibody against PSD4 was raised in rabbit using the Recombinant Human PH and SEC7 domain-containing protein 4 protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against PSD4 was raised in rabbit using the Recombinant Human PH and SEC7 domain-containing protein 4 protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human tonsil tissue using PSD4 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using PSD4 Antibody at dilution of 1:1002
| Cat.No | ADC-22524A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PSD4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human PH and SEC7 domain-containing protein 4 protein (1-300AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8NDX1 |
Uniprot Id
Q8NDX1
Target Species
Human
Target Name
PSD4
Target Full Name
PH and SEC7 domain-containing protein 4
Target Function
Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
Target Subcellular Location
Cell membrane. Cell projection, ruffle membrane.
Target Tissue Specificity
Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
Target Synonyms
EFA6B; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B; FLJ36237; FLJ37279; PH and SEC7 domain-containing protein 4; Pleckstrin homology and SEC7 domain-containing protein 4; Ppleckstrin and Sec7 domain containing 4 ; PSD4; PSD4_HUMAN; SEC7 homolog | telomeric of interleukin-1 cluster protein; Telomeric of interleukin-1 cluster protein; TIC
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