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The antibody against PWP1 was raised in rabbit using the Human PWP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against PWP1 was raised in rabbit using the Human PWP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-52168A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PWP1 |
| Target Synonyms | Keratinocyte protein IEF SSP 9502 antibody; Periodic tryptophan protein 1 homolog antibody; PWP1 antibody; PWP1 homolog antibody; PWP1_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human PWP1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13610 |
Uniprot Id
Q13610
Target Species
Human
Target Name
PWP1
Target Full Name
Periodic tryptophan protein 1 homolog
Target Function
Chromatin-associated factor that regulates transcription. Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription. Regulates the epigenetic status of rDNA.
Target Subcellular Location
Nucleus. Nucleus, nucleolus. Chromosome.
Target Protein Families
WD repeat PWP1 family
Target Tissue Specificity
High levels seen in the placenta, skeletal muscle, kidney and pancreas while lower levels were seen in the heart, brain and lung.
Target Synonyms
Keratinocyte protein IEF SSP 9502; Periodic tryptophan protein 1 homolog; PWP1; PWP1 homolog; PWP1_HUMAN
Target Background
The protein encoded by this gene contains several WD-40 repeats and is found mostly in the nucleus. The expression and localization of this protein are cell cycle dependent. Expression of this gene is upregulated in pancreatic adenocarcinoma. Three transcript variants encoding different isoforms have been found for this gene.
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