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The antibody against RABGEF1 was raised in rabbit using the Recombinant Human Rab5 GDP/GTP exchange factor protein (1-491AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RABGEF1 was raised in rabbit using the Recombinant Human Rab5 GDP/GTP exchange factor protein (1-491AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human brain tissue using RABGEF1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human endometrial cancer using RABGEF1 Antibody at dilution of 1:1002
| Cat.No | ADC-44050A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RABGEF1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Rab5 GDP/GTP exchange factor protein (1-491AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UJ41 |
Uniprot Id
Q9UJ41
Target Species
Human
Target Name
RABGEF1
Target Full Name
Rab5 GDP/GTP exchange factor
Target Function
Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.
Target Subcellular Location
Cytoplasm. Early endosome. Recycling endosome.
Target Research Area
Signal Transduction
Target Synonyms
RAB guanine nucleotide exchange factor (GEF) 1; Rab5 GDP/GTP exchange factor; Rab5ef; Rabaptin 5 associated exchange factor for Rab5; Rabaptin-5-associated exchange factor for Rab5; Rabex 5; Rabex-5; RABGEF 1; Rabgef1; RABX 5; RABX5; RABX5_HUMAN; RAP1; Rin 2; Rin2
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