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The antibody against RGN was raised in rabbit using the Human RGN,SMP30 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against RGN was raised in rabbit using the Human RGN,SMP30 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-51175A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RGN |
| Target Synonyms | Gluconolactonase antibody; GNL antibody; RC antibody; Regucalcin antibody; RGN antibody; RGN_HUMAN antibody; Senescence marker protein 30 antibody; SMP 30 antibody; SMP-30 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human RGN,SMP30 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15493 |
Uniprot Id
Q15493
Target Species
Human
Target Name
RGN
Target Full Name
Regucalcin
Target Function
Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities.
Target Subcellular Location
Cytoplasm.
Target Protein Families
SMP-30/CGR1 family
Target Synonyms
Gluconolactonase; GNL; RC; Regucalcin; RGN; RGN_HUMAN; Senescence marker protein 30; SMP 30 ; SMP-30
Target Background
The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in multiple transcript variants.
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