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The antibody against SOX3 was raised in rabbit using the Recombinant Human Transcription factor SOX-3 protein (4-118AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against SOX3 was raised in rabbit using the Recombinant Human Transcription factor SOX-3 protein (4-118AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-06755A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SOX3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transcription factor SOX-3 protein (4-118AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P41225 |
Uniprot Id
P41225
Target Species
Human
Target Name
SOX3
Target Full Name
Transcription factor SOX-3
Target Function
Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.
Target Involvement
Panhypopituitarism X-linked (PHPX); Mental retardation, X-linked, with isolated growth hormone deficiency (MRXGH); 46,XX sex reversal 3 (SRXX3)
Target Subcellular Location
Nucleus.
Target Synonyms
GHDX; MRGH; PHP; PHPX; sox3; SOX3_HUMAN; SOXB; SRY (sex determining region Y)-box 3; SRY Box 3; SRY-related HMG-box gene 3; Transcription factor Sox-3
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