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The antibody against SPIN2B was raised in rabbit using the Recombinant Human Spindlin-2B protein (1-258AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against SPIN2B was raised in rabbit using the Recombinant Human Spindlin-2B protein (1-258AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human breast cancer using SPIN2B Antibody at dilution of 1:1002
| Cat.No | ADC-44081A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPIN2B |
| Target Synonyms | SPIN2B antibody; SPIN2 antibody; Spindlin-2B antibody; Spindlin-like protein 2B antibody; SPIN-2 antibody; SPIN-2B antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Spindlin-2B protein (1-258AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BPZ2 |
Uniprot Id
Q9BPZ2
Target Species
Human
Target Name
SPIN2B
Target Full Name
Spindlin-2B
Target Function
Involved in the regulation of cell cycle progression, this activity is related to the inhibition of apoptosis following the removal of essential growth factors. Exhibits H3K4me3-binding activity.
Target Subcellular Location
Nucleus.
Target Protein Families
SPIN/STSY family
Target Tissue Specificity
Detected in all the examined tissues with highest expression in liver, followed by heart, stomach, kidney, skeletal muscle, placenta, and pancreas.
Target Research Area
others
Target Synonyms
SPIN2B; SPIN2; Spindlin-2B; Spindlin-like protein 2B; SPIN-2; SPIN-2B
Target Background
Enables methylated histone binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Located in cytosol and nucleoplasm.
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