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The antibody against SPRR1A was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-89 of human SPRR1A (NP_005978.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against SPRR1A was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-89 of human SPRR1A (NP_005978.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-10500A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPRR1A |
| Target Synonyms | SPRK; SPRR1A | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse stomach | Application | ELISA, WB, IF/ICC |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 1-89 of human SPRR1A (NP_005978.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MNSQQQKQPCTPPPQPQQQQVKQPCQPPPQEPCIPKTKEPCHPKVPEPCHPKVPEPCQPKVPEPCQPKVPEPCPSTVTPAPAQQKTKQK | Uniprot ID | P35321 |
Uniprot Id
P35321
Target Species
Human
Target Name
SPRR1A
Target Full Name
Cornifin-A
Target Function
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Cornifin (SPRR) family
Target Research Area
Neuroscience
Target Synonyms
SPRR1A; Cornifin-A; 19 kDa pancornulin; SPRK; Small proline-rich protein IA; SPR-IA
Target Background
A structural constituent of skin epidermis. Involved in keratinocyte differentiation and peptide cross-linking. Located in cornified envelope.
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