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Rabbit anti-Human SRM Polyclonal Antibody

The antibody against SRM was raised in rabbit using the Human SRM as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.

ADC-51746A

The antibody against SRM was raised in rabbit using the Human SRM as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.

$600.00

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Specifications


Cat.No ADC-51746A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSRM
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman SRMTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP19623
Background Information
  • Uniprot Id

    P19623

  • Target Species

    Human

  • Target Name

    SRM

  • Target Full Name

    Spermidine synthase

  • Target Function

    Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.

  • Target Protein Families

    Spermidine/spermine synthase family

  • Target Research Area

    Metabolism

  • Target Synonyms

    OTTHUMP00000002170; PAPT; Putrescine aminopropyltransferase; SPDSY; SPEE_HUMAN; Spermidine synthase 1; Spermidine synthase; SPS1; Srm; SRML1

  • Target Background

    The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.

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