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The antibody against SRR was raised in rabbit using the Recombinant Human Serine racemase protein (1-340AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against SRR was raised in rabbit using the Recombinant Human Serine racemase protein (1-340AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human heart tissue using SRR Antibody at dilution of 1:1002
| Cat.No | ADC-10759A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRR |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Serine racemase protein (1-340AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9GZT4 |
Uniprot Id
Q9GZT4
Target Species
Human
Target Name
SRR
Target Full Name
Serine racemase
Target Function
Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Target Protein Families
Serine/threonine dehydratase family
Target Tissue Specificity
Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.
Target Research Area
Neuroscience
Target Synonyms
D serine ammonia lyase; D serine dehydratase; D-serine ammonia-lyase; D-serine dehydratase; ILV1; ISO1; L serine ammonia lyase; L serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; Serine racemase; srr; SRR_HUMAN
Target Background
Enables several functions, including L-serine ammonia-lyase activity; PDZ domain binding activity; and anion binding activity. Involved in pyruvate biosynthetic process; response to lipopolysaccharide; and serine family amino acid metabolic process. Located in cytoplasm and neuronal cell body.
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