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The antibody against TGM5 was raised in rabbit using the Synthetic peptide of Human TGM5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against TGM5 was raised in rabbit using the Synthetic peptide of Human TGM5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-25709A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TGM5 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human TGM5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43548 |
Uniprot Id
O43548
Target Species
Human
Target Name
TGM5
Target Full Name
Protein-glutamine gamma-glutamyltransferase 5
Target Function
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.
Target Involvement
Peeling skin syndrome 2 (PSS2)
Target Subcellular Location
Cytoplasm. Note=Associated with intermediate filaments.
Target Protein Families
Transglutaminase superfamily, Transglutaminase family
Target Tissue Specificity
Expressed in foreskin keratinocytes.
Target Synonyms
Protein glutamine gamma glutamyltransferase 5; Protein-glutamine gamma-glutamyltransferase 5; PSS2; TG(X); TGase 5; TGase X; TGase-5; TGase5; TGASEX; Tgm5; TGM5_HUMAN; TGM6; TGMX; TGX; Transglutaminase X; Transglutaminase-5
Target Background
This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome.
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