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Rabbit anti-Human THBS1 Polyclonal Antibody

The antibody against THBS1 was raised in rabbit using the Recombinant Human Thrombospondin-1 protein (19-350AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-50575A

The antibody against THBS1 was raised in rabbit using the Recombinant Human Thrombospondin-1 protein (19-350AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-50575A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTHBS1
Target SynonymsTHBS 1 antibody; THBS antibody; Thbs1 antibody; Thrombospondin 1 antibody; Thrombospondin-1 antibody; TSP 1 antibody; TSP antibody; TSP1 antibody; TSP1_HUMAN antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Thrombospondin-1 protein (19-350AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP07996
Background Information
  • Uniprot Id

    P07996

  • Target Species

    Human

  • Target Name

    THBS1

  • Target Full Name

    Thrombospondin-1

  • Target Function

    Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp. Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors.

  • Target Subcellular Location

    Secreted. Cell surface. Secreted, extracellular space, extracellular matrix. Endoplasmic reticulum. Sarcoplasmic reticulum.

  • Target Protein Families

    Thrombospondin family

  • Target Research Area

    Cell Adhesion

  • Target Synonyms

    THBS 1; THBS; Thbs1; Thrombospondin 1; Thrombospondin-1; TSP 1; TSP; TSP1; TSP1_HUMAN

  • Target Background

    The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.

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