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The antibody against TK1 was raised in rabbit using the Recombinant Human Thymidine kinase, cytosolic protein (1-234AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against TK1 was raised in rabbit using the Recombinant Human Thymidine kinase, cytosolic protein (1-234AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human breast cancer using TK1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue using TK1 Antibody at dilution of 1:1002
| Cat.No | ADC-44583A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TK1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Thymidine kinase, cytosolic protein (1-234AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04183 |
Uniprot Id
P04183
Target Species
Human
Target Name
TK1
Target Full Name
Thymidine kinase, cytosolic
Target Subcellular Location
Cytoplasm.
Target Protein Families
Thymidine kinase family
Target Synonyms
TK2; Thymidine Kinase 1
Target Background
The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers.
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