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The antibody against TOB1 was raised in rabbit using the Synthesized non-phosphopeptide derived from Human TOB1 around the phosphorylation site of serine 164 (A-V-S(p)-P-T). as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against TOB1 was raised in rabbit using the Synthesized non-phosphopeptide derived from Human TOB1 around the phosphorylation site of serine 164 (A-V-S(p)-P-T). as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
$297.00
Western blot analysis of extracts from HT-29 cells, treated with serum (20%, 15mins), using TOB1 (Ab-164) antibody.
Immunohistochemistry analysis of paraffin-embedded human brain tissue using TOB1 (Ab-164) antiobdy.2
| Cat.No | ADC-42488A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TOB1 |
| Target Synonyms | TOB1 antibody; TOB antibody; TROB1 antibody; Protein Tob1 antibody; Transducer of erbB-2 1 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized non-phosphopeptide derived from Human TOB1 around the phosphorylation site of serine 164 (A-V-S(p)-P-T). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P50616 |
Uniprot Id
P50616
Target Species
Human
Target Name
TOB1
Target Full Name
Protein Tob1
Target Function
Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
BTG family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
TOB1; TOB; TROB1; Protein Tob1; Transducer of erbB-2 1
Target Background
This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants.
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