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The antibody against TRPM6 was raised in rabbit using the Synthetic peptide of Human TRPM6 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against TRPM6 was raised in rabbit using the Synthetic peptide of Human TRPM6 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-25616A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRPM6 |
| Target Synonyms | TRPM6 antibody; CHAK2Transient receptor potential cation channel subfamily M member 6 antibody; EC 2.7.11.1 antibody; Channel kinase 2 antibody; Melastatin-related TRP cation channel 6 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human TRPM6 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BX84 |
Uniprot Id
Q9BX84
Target Species
Human
Target Name
TRPM6
Target Full Name
Transient receptor potential cation channel subfamily M member 6
Target Function
Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region.
Target Involvement
Hypomagnesemia 1 (HOMG1)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient receptor (TC 1.A.4) family, LTrpC subfamily, TRPM6 sub-subfamily
Target Tissue Specificity
Highly expressed in kidney and colon. Isoform TRPM6a and isoform TRPM6b, are coexpressed with TRPM7 in kidney, and testis, and are also found in several cell lines of lung origin. Isoform TRPM6c is detected only in testis and in NCI-H510A small cell lung
Target Synonyms
TRPM6; CHAK2Transient receptor potential cation channel subfamily M member 6; EC 2.7.11.1; Channel kinase 2; Melastatin-related TRP cation channel 6
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