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The antibody against TSHB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 21-138 of human TSHB (NP_000540.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against TSHB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 21-138 of human TSHB (NP_000540.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
Immunohistochemistry analysis of paraffin-embedded human prostate using TSHB antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
| Cat.No | ADA-02847A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TSHB |
| Target Synonyms | TSH-B; TSH-BETA; TSHB | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 21-138 of human TSHB (NP_000540.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | FCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGFSV | Uniprot ID | P01222 |
Uniprot Id
P01222
Target Species
Human
Target Name
TSHB
Target Full Name
Thyrotropin subunit beta
Target Function
Indispensable for the control of thyroid structure and metabolism.
Target Subcellular Location
Secreted.
Target Protein Families
Glycoprotein hormones subunit beta family
Target Research Area
Signal Transduction
Target Synonyms
TSHBThyrotropin subunit beta; Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chain; Thyrotropin alfa
Target Background
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.
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