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Rabbit anti-Human UGT2B4 Polyclonal Antibody

The antibody against UGT2B4 was raised in rabbit using the Fusion protein of Human UGT2B4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-28993A

The antibody against UGT2B4 was raised in rabbit using the Fusion protein of Human UGT2B4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-28993A ClonalityPolyclonal
Host SpeciesRabbitTarget NameUGT2B4
Target SynonymsUGT2B4 antibody; UGT2B11 antibody; UDP-glucuronosyltransferase 2B4 antibody; UDPGT 2B4 antibody; EC 2.4.1.17 antibody; HLUG25 antibody; Hyodeoxycholic acid-specific UDPGT antibody; UDPGTh-1 antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human UGT2B4Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP06133
Background Information
  • Uniprot Id

    P06133

  • Target Species

    Human

  • Target Name

    UGT2B4

  • Target Full Name

    UDP-glucuronosyltransferase 2B4

  • Target Function

    UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Catalyzes the glucuronidation of the endogenous estrogen hormones such as estradiol and estriol.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Single-pass membrane protein.

  • Target Protein Families

    UDP-glycosyltransferase family

  • Target Synonyms

    UGT2B4; UGT2B11; UDP-glucuronosyltransferase 2B4; UDPGT 2B4; EC 2.4.1.17; HLUG25; Hyodeoxycholic acid-specific UDPGT; UDPGTh-1

  • Target Background

    Enables glucuronosyltransferase activity. Involved in cellular glucuronidation and estrogen metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle.

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