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Rabbit anti-Human VPS37D Polyclonal Antibody

The antibody against VPS37D was raised in rabbit using the Fusion protein of Human VPS37D as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-28930A

The antibody against VPS37D was raised in rabbit using the Fusion protein of Human VPS37D as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-28930A ClonalityPolyclonal
Host SpeciesRabbitTarget NameVPS37D
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human VPS37DTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ86XT2
Background Information
  • Uniprot Id

    Q86XT2

  • Target Species

    Human

  • Target Name

    VPS37D

  • Target Full Name

    Vacuolar protein sorting-associated protein 37D

  • Target Function

    Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.

  • Target Involvement

    VPS37D is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.

  • Target Subcellular Location

    Late endosome membrane; Peripheral membrane protein.

  • Target Protein Families

    VPS37 family

  • Target Synonyms

    ESCRT-I complex subunit VPS37D; MGC35352; Vacuolar protein sorting-associated protein 37D; VP37D_HUMAN; VPS37D; WBSCR24; Williams-Beuren syndrome chromosomal region 24 protein

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