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The antibody against Epn2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse Epn2 (XP_006532226.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against Epn2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse Epn2 (XP_006532226.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00165A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EPN2 |
| Target Synonyms | Ibp2; 9530051D10Rik; Epn2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2 | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse Epn2 (XP_006532226.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | IFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSTSYSEQEYGKAGGSPASYHGSP | Uniprot ID | O95208 |
Uniprot Id
O95208
Target Species
Human
Target Name
EPN2
Target Full Name
Epsin-2
Target Function
Plays a role in the formation of clathrin-coated invaginations and endocytosis.
Target Subcellular Location
Cytoplasm. Cytoplasmic vesicle, clathrin-coated vesicle. Note=In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.
Target Protein Families
Epsin family
Target Tissue Specificity
Highest expression is found in brain. Detected at lower levels in lung and liver.
Target Synonyms
EHB21; EPN 2; Epn2; EPN2_HUMAN; EPS 15 interacting protein 2; EPS-15-interacting protein 2; Eps15 binding protein; Epsin 2; Epsin-2; Epsin2; KIAA1065; OTTHUMP00000065808; OTTHUMP00000065809; OTTHUMP00000065810; OTTHUMP00000065811; OTTHUMP00000065889
Target Background
Predicted to enable clathrin binding activity and phospholipid binding activity. Acts upstream of or within Notch signaling pathway; embryonic organ development; and in utero embryonic development. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of clathrin coat of endocytic vesicle. Predicted to be active in endosome and plasma membrane. Orthologous to human EPN2 (epsin 2).
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