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Rabbit anti-Mus musculus (Mouse) Ltbp1 Polyclonal Antibody, HRP conjugated

The antibody against Ltbp1 was raised in rabbit using the Recombinant Mouse Latent-transforming growth factor beta-binding protein 1 protein (20-299AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-11336A

The antibody against Ltbp1 was raised in rabbit using the Recombinant Mouse Latent-transforming growth factor beta-binding protein 1 protein (20-299AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-11336A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLtbp1
Target SynonymsLtbp1Latent-transforming growth factor beta-binding protein 1 antibody; LTBP-1 antibody; Transforming growth factor beta-1-binding protein 1 antibody; TGF-beta1-BP-1 antibodyFormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateHRP conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Mouse Latent-transforming growth factor beta-binding protein 1 protein (20-299AA)Target SpeciesMus musculus (Mouse)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8CG19
Background Information
  • Uniprot Id

    Q8CG19

  • Target Species

    Mouse

  • Target Name

    LTBP1

  • Target Full Name

    Latent-transforming growth factor beta-binding protein 1

  • Target Function

    Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta.

  • Target Subcellular Location

    Secreted. Secreted, extracellular space, extracellular matrix.

  • Target Protein Families

    LTBP family

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