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The antibody against Kcne2 was raised in rabbit using the Recombinant Rat Potassium voltage-gated channel subfamily E member 2 protein (1-123AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Kcne2 was raised in rabbit using the Recombinant Rat Potassium voltage-gated channel subfamily E member 2 protein (1-123AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-50194A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Kcne2 |
| Form | Liquid | Species Reactivity | Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Rat Potassium voltage-gated channel subfamily E member 2 protein (1-123AA) | Target Species | Rattus norvegicus (Rat) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P63161 |
Uniprot Id
P63161
Target Species
Rat
Target Name
KCNE2
Target Full Name
Potassium voltage-gated channel subfamily E member 2
Target Function
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current. May associate with HCN1 and HCN2 and increase potassium current. Interacts with KCNQ1; forms a heterooligomer complex leading to currents with an apparently instantaneous activation, a rapid deactivation process and a linear current-voltage relationship and decreases the amplitude of the outward current.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Potassium channel KCNE family
Target Tissue Specificity
Expressed in the heart.
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