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The antibody against ECSCR was raised in rabbit using the Recombinant Human Endothelial cell-specific chemotaxis regulator protein (25-124AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ECSCR was raised in rabbit using the Recombinant Human Endothelial cell-specific chemotaxis regulator protein (25-124AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human lung tissue using ECSCR Antibody at dilution of 1:100
| Cat.No | ADC-09176A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ECSCR |
| Target Synonyms | ECSCR antibody; ECSCR_HUMAN antibody; Endothelial cell-specific chemotaxis regulator antibody; Endothelial cell-specific molecule 2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Endothelial cell-specific chemotaxis regulator protein (25-124AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q19T08 |
Uniprot Id
Q19T08
Target Species
Human
Target Name
ECSCR
Target Full Name
Endothelial cell-specific chemotaxis regulator
Target Function
Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Target Protein Families
ECSCR family
Target Tissue Specificity
Highest expression in endothelial cells. Also detected in vascular smooth muscle, macrophages, lymphocytes, and mast cells.
Target Synonyms
ECSCR; ECSCR_HUMAN; Endothelial cell-specific chemotaxis regulator; Endothelial cell-specific molecule 2
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