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The antibody against IL26 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human IL-26. as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against IL26 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human IL-26. as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western blot analysis of RAT-MUSLE RAT-SPLEEN 293T SH-SY5Y using IL26 antibody. Antibody was diluted at 1:2000. Secondary antibody was diluted at 1:20000
| Cat.No | ADC-13134A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IL26 |
| Target Synonyms | AK155 antibody; IL 26 antibody; IL-26 antibody; IL26 antibody; IL26_HUMAN antibody; Interleukin 26 antibody; Interleukin-26 antibody; Protein AK155 antibody | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human IL-26. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NPH9 |
Uniprot Id
Q9NPH9
Target Species
Human
Target Name
IL26
Target Full Name
Interleukin-26
Target Function
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
Target Subcellular Location
Secreted.
Target Protein Families
IL-10 family
Target Tissue Specificity
Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protei
Target Research Area
Immunology
Target Synonyms
AK155; IL 26; IL-26; IL26; IL26_HUMAN; Interleukin 26; Interleukin-26; Protein AK155
Target Background
This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri.
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