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The antibody against NDUFAF1 was raised in rabbit using the Recombinant Human Complex I intermediate-associated protein 30, mitochondrial protein (25-327AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against NDUFAF1 was raised in rabbit using the Recombinant Human Complex I intermediate-associated protein 30, mitochondrial protein (25-327AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using NDUFAF1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using NDUFAF1 Antibody at dilution of 1:1002
| Cat.No | ADC-17646A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NDUFAF1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Complex I intermediate-associated protein 30, mitochondrial protein (25-327AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y375 |
Uniprot Id
Q9Y375
Target Species
Human
Target Name
NDUFAF1
Target Full Name
Complex I intermediate-associated protein 30, mitochondrial
Target Function
Chaperone protein involved in early stages of the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
Target Subcellular Location
Mitochondrion. Mitochondrion matrix.
Target Protein Families
CIA30 family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
CGI 65; CGI65; CIA30; CIA30_HUMAN; Complex I intermediate associated protein 30; Complex I intermediate associated protein 30 mitochondrial; Complex I intermediate-associated protein 30; mitochondrial; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor 1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1; NADH:ubiquinone oxidoreductase complex assembly factor 1; NDUFAF 1; Ndufaf1
Target Background
This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19.
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