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The antibody against SELENOM was raised in rabbit using the Recombinant Human Selenoprotein M protein (49-145AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against SELENOM was raised in rabbit using the Recombinant Human Selenoprotein M protein (49-145AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-18932A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SELENOM |
| Target Synonyms | SELENOM antibody; SELM antibody; Selenoprotein M antibody; SelM antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Selenoprotein M protein (49-145AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WWX9 |
Uniprot Id
Q8WWX9
Target Species
Human
Target Name
SELENOM
Target Full Name
Selenoprotein M
Target Function
May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation.
Target Subcellular Location
Cytoplasm, perinuclear region. Endoplasmic reticulum. Golgi apparatus. Note=Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum.
Target Protein Families
Selenoprotein M/F family
Target Tissue Specificity
Widely expressed.
Target Research Area
Others
Target Synonyms
SELENOM; SELM; Selenoprotein M; SelM
Target Background
The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.
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