Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against CNGA4 was raised in rabbit using the Recombinant Human Cyclic nucleotide-gated cation channel alpha-4 protein (1-575AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CNGA4 was raised in rabbit using the Recombinant Human Cyclic nucleotide-gated cation channel alpha-4 protein (1-575AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CNGA4 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using CNGA4 Antibody at dilution of 1:1002
| Cat.No | ADC-19326A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CNGA4 |
| Target Synonyms | CNGA4; Cyclic nucleotide-gated cation channel alpha-4; Cyclic nucleotide-gated channel alpha-4; CNG channel alpha-4; CNG-4; CNG4 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cyclic nucleotide-gated cation channel alpha-4 protein (1-575AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IV77 |
Uniprot Id
Q8IV77
Target Species
Human
Target Name
CNGA4
Target Full Name
Cyclic nucleotide-gated channel alpha-4
Target Function
Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Cyclic nucleotide-gated cation channel (TC 1.A.1.5) family, CNGA4 subfamily
Target Synonyms
CNGA4; Cyclic nucleotide-gated cation channel alpha-4; Cyclic nucleotide-gated channel alpha-4; CNG channel alpha-4; CNG-4; CNG4
Target Background
CNGA4 is a modulatory subunit of vertebrate cyclic nucleotide-gated membrane channels that transduce odorant signals (Munger et al., 2001 [PubMed 11739959]).
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
