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The antibody against RUFY4 was raised in rabbit using the Recombinant Human RUN and FYVE domain-containing protein 4 protein (174-473AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RUFY4 was raised in rabbit using the Recombinant Human RUN and FYVE domain-containing protein 4 protein (174-473AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using RUFY4 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using RUFY4 Antibody at dilution of 1:1002
| Cat.No | ADC-19684A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RUFY4 |
| Target Synonyms | RUFY4RUN and FYVE domain-containing protein 4 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human RUN and FYVE domain-containing protein 4 protein (174-473AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6ZNE9 |
Uniprot Id
Q6ZNE9
Target Species
Human
Target Name
RUFY4
Target Full Name
RUN and FYVE domain-containing protein 4
Target Function
Positively regulates macroautophagy in primary dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE-type zinc finger.
Target Subcellular Location
Cytoplasmic vesicle, autophagosome.
Target Synonyms
RUFY4RUN and FYVE domain-containing protein 4
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