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The antibody against ZMYM3 was raised in rabbit using the Recombinant Human Zinc finger MYM-type protein 3 protein (1-495AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against ZMYM3 was raised in rabbit using the Recombinant Human Zinc finger MYM-type protein 3 protein (1-495AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
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Immunofluorescent analysis of A549 cells using ZMYM3 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
| Cat.No | ADC-20334A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZMYM3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Zinc finger MYM-type protein 3 protein (1-495AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14202 |
Uniprot Id
Q14202
Target Species
Human
Target Name
ZMYM3
Target Full Name
Zinc finger MYM-type protein 3
Target Function
Plays a role in the regulation of cell morphology and cytoskeletal organization.
Target Involvement
A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?).
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Most abundant in brain, moderate in muscle and heart, low in other tissues except placenta.
Target Synonyms
DXS6673E; KIAA0385; MYM; XFIM; ZFP261; Zinc finger MYM type 3; Zinc finger MYM type protein 3; Zinc finger MYM-type protein 3; Zinc finger protein 261; ZMYM 3; Zmym3; ZMYM3_HUMAN; ZNF 261; ZNF198L2; ZNF261
Target Background
This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene.
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