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The antibody against Irf5 was raised in rabbit using the Recombinant Mouse Interferon regulatory factor 5 protein (1-497AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Irf5 was raised in rabbit using the Recombinant Mouse Interferon regulatory factor 5 protein (1-497AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-21974A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IRF5 |
| Target Synonyms | Irf5Interferon regulatory factor 5 antibody; IRF-5 antibody | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Interferon regulatory factor 5 protein (1-497AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P56477 |
Uniprot Id
P56477
Target Species
Mouse
Target Name
IRF5
Target Full Name
Interferon regulatory factor 5
Target Function
Transcription factor that plays a critical role in innate immunity by activating expression of type I interferon (IFN) IFNA and INFB and inflammatory cytokines downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction downstream of the TLR-activated, MyD88-dependent pathway.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
IRF family
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