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The antibody against IDI2 was raised in rabbit using the Recombinant Human Isopentenyl-diphosphate delta-isomerase 2 protein (1-227AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against IDI2 was raised in rabbit using the Recombinant Human Isopentenyl-diphosphate delta-isomerase 2 protein (1-227AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human breast cancer using IDI2 Antibody at dilution of 1:100
| Cat.No | ADC-24695A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IDI2 |
| Target Synonyms | IDI2 antibody; Isopentenyl-diphosphate delta-isomerase 2 antibody; EC 5.3.3.2 antibody; Isopentenyl pyrophosphate isomerase 2 antibody; IPP isomerase 2 antibody; IPPI2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Isopentenyl-diphosphate delta-isomerase 2 protein (1-227AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BXS1 |
Uniprot Id
Q9BXS1
Target Species
Human
Target Name
IDI2
Target Full Name
Isopentenyl-diphosphate delta-isomerase 2
Target Function
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
Target Subcellular Location
Peroxisome.
Target Protein Families
IPP isomerase type 1 family
Target Tissue Specificity
Muscle-specific expression.
Target Synonyms
IDI2; Isopentenyl-diphosphate delta-isomerase 2; EC 5.3.3.2; Isopentenyl pyrophosphate isomerase 2; IPP isomerase 2; IPPI2
Target Background
The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis.
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