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The antibody against HBD was raised in rabbit using the Recombinant Human Hemoglobin subunit delta protein (2-147AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against HBD was raised in rabbit using the Recombinant Human Hemoglobin subunit delta protein (2-147AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human small intestine tissue using HBD Antibody at dilution of 1:100
| Cat.No | ADC-24766A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HBD |
| Target Synonyms | Delta-globin antibody; HBD antibody; HBD_HUMAN antibody; Hemoglobin delta chain antibody; Hemoglobin subunit delta antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Hemoglobin subunit delta protein (2-147AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P02042 |
Uniprot Id
P02042
Target Species
Human
Target Name
HBD
Target Full Name
Hemoglobin subunit delta
Target Function
Involved in oxygen transport from the lung to the various peripheral tissues.
Target Protein Families
Globin family
Target Tissue Specificity
Red blood cells.
Target Research Area
Transport
Target Synonyms
Delta-globin; HBD; HBD_HUMAN; Hemoglobin delta chain; Hemoglobin subunit delta
Target Background
The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia.
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