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The antibody against CMTR2 was raised in rabbit using the Recombinant Human Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 protein (301-600AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against CMTR2 was raised in rabbit using the Recombinant Human Cap-specific mRNA (nucleoside-2′-O-)-methyltransferase 2 protein (301-600AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human skin tissue using CMTR2 Antibody at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using CMTR2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-25114A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CMTR2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 protein (301-600AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IYT2 |
Uniprot Id
Q8IYT2
Target Species
Human
Target Name
CMTR2
Target Full Name
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2
Target Function
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Synonyms
CMTR2; AFT; FTSJD1; Cap-specific mRNA; nucleoside-2'-O--methyltransferase 2; Cap methyltransferase 2; Cap2 2'O-ribose methyltransferase 2; HMTr2; MTr2; FtsJ methyltransferase domain-containing protein 1; Protein adrift homolog
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