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Rabbit anti-Human MYO3B Polyclonal Antibody

The antibody against MYO3B was raised in rabbit using the Recombinant Human Myosin-IIIb protein (1110-1276AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-03207A

The antibody against MYO3B was raised in rabbit using the Recombinant Human Myosin-IIIb protein (1110-1276AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-03207A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMYO3B
Target SynonymsA430065P19Rik antibody; Myo3b antibody; MYO3B_HUMAN antibody; Myosin IIIB antibody; Myosin-IIIB antibody; RGD1560313 antibody; RP23-337L20.2 antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Myosin-IIIb protein (1110-1276AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8WXR4
Background Information
  • Uniprot Id

    Q8WXR4

  • Target Species

    Human

  • Target Name

    MYO3B

  • Target Full Name

    Myosin-IIIb

  • Target Function

    Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments.

  • Target Subcellular Location

    Cytoplasm, cytoskeleton. Cell projection, stereocilium.

  • Target Protein Families

    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family

  • Target Tissue Specificity

    Expressed in retina, kidney and testis.

  • Target Synonyms

    A430065P19Rik; Myo3b; MYO3B_HUMAN; Myosin IIIB; Myosin-IIIB; RGD1560313; RP23-337L20.2

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