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Rabbit anti-Human TLR13 Polyclonal Antibody

The antibody against Tlr13 was raised in rabbit using the Recombinant Protein as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on IHC, ELISA.

ADC-33132A

The antibody against Tlr13 was raised in rabbit using the Recombinant Protein as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-33132A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTlr13
Target SynonymsTlr13 antibody; Toll-like receptor 13 antibody; EC 3.2.2.6 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage BufferPH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBSConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant ProteinTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6R5N8
Background Information
  • Uniprot Id

    Q6R5N8

  • Target Species

    Human

  • Target Name

    TLR13

  • Target Function

    Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin). May also recognize vesicular stomatitis virus; however, these data require additional evidences.

  • Target Subcellular Location

    Endosome membrane; Single-pass type I membrane protein.

  • Target Protein Families

    Toll-like receptor family

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