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The antibody against TECR was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human GPSN2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against TECR was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human GPSN2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
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Western blot analysis of 293T lysis using GPSN2 antibody.
| Cat.No | ADC-33285A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TECR |
| Target Synonyms | 3-enoyl-CoA reductase; TER, TECR; GPSN2; SC2; Very-long-chain enoyl-CoA reductase; Synaptic glycoprotein SC2; Trans-2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human GPSN2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NZ01 |
Uniprot Id
Q9NZ01
Target Species
Human
Target Name
TECR
Target Full Name
Very-long-chain enoyl-CoA reductase
Target Function
Involved in both the production of very long-chain fatty acids for sphingolipid synthesis and the degradation of the sphingosine moiety in sphingolipids through the sphingosine 1-phosphate metabolic pathway. Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Catalyzes the saturation step of the sphingosine 1-phosphate metabolic pathway, the conversion of trans-2-hexadecenoyl-CoA to palmitoyl-CoA.
Target Involvement
Mental retardation, autosomal recessive 14 (MRT14)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
Steroid 5-alpha reductase family
Target Tissue Specificity
Expressed in most tissues tested. Highly expressed in skeletal muscle.
Target Research Area
Signal Transduction
Target Synonyms
TECR; GPSN2; SC2; Very-long-chain enoyl-CoA reductase; Synaptic glycoprotein SC2; Trans-2,3-enoyl-CoA reductase; TER
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