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The antibody against FANCG was raised in rabbit using the Synthesized peptide derived from Human FANCG around the phosphorylation site of S383. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against FANCG was raised in rabbit using the Synthesized peptide derived from Human FANCG around the phosphorylation site of S383. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of K562 cells using Phospho-FANCG (S383) Polyclonal Antibody
| Cat.No | ADC-35933A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FANCG |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Human FANCG around the phosphorylation site of S383. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O15287 |
Uniprot Id
O15287
Target Species
Human
Target Name
FANCG
Target Full Name
Fanconi anemia group G protein
Target Function
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
Target Involvement
Fanconi anemia complementation group G (FANCG)
Target Subcellular Location
Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
Target Tissue Specificity
Highly expressed in testis and thymus. Found in lymphoblasts.
Target Synonyms
DNA repair protein XRCC9; FAG; FANCG; FANCG_HUMAN; Fanconi anaemia complementation group G; Fanconi anemia group G protein; Protein FACG; X ray repair; complementing defective; in Chinese hamster cells 9; X-ray repair; complementing defective; in Chinese hamster; 9; XRCC9
Target Background
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
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