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Rabbit anti-Human ACOT2 Polyclonal Antibody

The antibody against ACOT2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human ACOT2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

ADC-36542A

The antibody against ACOT2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human ACOT2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

$167.00

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Specifications


Cat.No ADC-36542A ClonalityPolyclonal
Host SpeciesRabbitTarget NameACOT2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human ACOT2.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP49753
Background Information
  • Uniprot Id

    P49753

  • Target Species

    Human

  • Target Name

    ACOT2

  • Target Full Name

    Acyl-coenzyme A thioesterase 2, mitochondrial

  • Target Function

    Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays higher activity toward long chain acyl CoAs (C14-C20). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria.

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    C/M/P thioester hydrolase family

  • Target Tissue Specificity

    Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas.

  • Target Synonyms

    ACOT2; PTE2; PTE2AAcyl-coenzyme A thioesterase 2; mitochondrial; Acyl-CoA thioesterase 2; EC 3.1.2.2; Acyl-coenzyme A thioester hydrolase 2a; CTE-Ia; Long-chain acyl-CoA thioesterase 2; ZAP128

  • Target Background

    This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants.

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