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The antibody against UBR3 was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase UBR3 protein (960-1113AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against UBR3 was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase UBR3 protein (960-1113AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-03990A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UBR3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human E3 ubiquitin-protein ligase UBR3 protein (960-1113AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6ZT12 |
Uniprot Id
Q6ZT12
Target Species
Human
Target Name
UBR3
Target Full Name
E3 ubiquitin-protein ligase UBR3
Target Function
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May play a role in Shh signaling by mediating the ubiquitination of Kif7. May be important for MYH9 function in certain tissues, possibly by regulating the ubiquitination of MYH9 and consequently affecting its interaction with MYO7A.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
UBR1 family
Target Synonyms
DKFZp434P117; DKFZp686N10185; E3 ubiquitin-protein ligase UBR3; FLJ37422; KIAA2024; MGC126489; N-recognin-3; Ubiquitin-protein ligase E3-alpha-3; Ubiquitin-protein ligase E3-alpha-III; Ubr3; UBR3_HUMAN; Zinc finger protein 650; ZNF 650; ZNF650
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