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The antibody against ANXA7 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Annexin VII. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against ANXA7 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Annexin VII. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of A549 cells using Annexin VII Polyclonal Antibody.
| Cat.No | ADC-36989A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ANXA7 |
| Target Synonyms | Annexin A7 antibody; Annexin VII antibody; Annexin-7 antibody; ANX7 antibody; ANXA7 antibody; ANXA7_HUMAN antibody; SNX antibody; Synexin antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human Annexin VII. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P20073 |
Uniprot Id
P20073
Target Species
Human
Target Name
ANXA7
Target Full Name
Annexin A7
Target Function
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.
Target Protein Families
Annexin family
Target Tissue Specificity
Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta.
Target Synonyms
Annexin A7; Annexin VII; Annexin-7; ANX7; ANXA7; ANXA7_HUMAN; SNX ; Synexin
Target Background
Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
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