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The antibody against FOSB was raised in rabbit using the Synthesized peptide derived from Human Fos B around the non-phosphorylation site of S27. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against FOSB was raised in rabbit using the Synthesized peptide derived from Human Fos B around the non-phosphorylation site of S27. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
$167.00
Western Blot analysis of 293 cells using Fos B Polyclonal Antibody
| Cat.No | ADC-38661A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FOSB |
| Form | Liquid | Species Reactivity | Human, Mouse, Monkey |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Human Fos B around the non-phosphorylation site of S27. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P53539 |
Uniprot Id
P53539
Target Species
Human
Target Name
FOSB
Target Full Name
Protein FosB
Target Function
FosB interacts with Jun proteins enhancing their DNA binding activity.
Target Subcellular Location
Nucleus.
Target Protein Families
BZIP family, Fos subfamily
Target Research Area
Cancer
Target Synonyms
Activator protein 1; AP 1; DKFZp686C0818; FBJ murine osteosarcoma viral oncogene homolog B; fosB; FOSB_HUMAN; G0/G1 switch regulatory protein 3; G0S3; GOS 3; GOS B; GOS3; GOSB; MGC42291; Oncogene FOS B; Oncogene FOSB; Protein fos B; Protein fosB
Target Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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