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The antibody against CPA1 was raised in rabbit using the Recombinant Human Carboxypeptidase A1 protein (111-419AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against CPA1 was raised in rabbit using the Recombinant Human Carboxypeptidase A1 protein (111-419AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using CPA1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CPA1 Antibody at dilution of 1:1002
| Cat.No | ADC-40540A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CPA1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Carboxypeptidase A1 protein (111-419AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P15085 |
Uniprot Id
P15085
Target Species
Human
Target Name
CPA1
Target Full Name
Carboxypeptidase A1
Target Function
Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond.
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase M14 family
Target Synonyms
carboxypeptidase A1 (pancreatic); Carboxypeptidase A1; Carboxypeptidase A1 precursor; CBPA1_HUMAN; CPA; CPA1; Pancreatic carboxypeptidase A1; Procarboxypeptidase A1 pancreatic
Target Background
This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer.
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