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The antibody against HCCS was raised in rabbit using the Synthesized peptide derived from internal of Human CCHL. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against HCCS was raised in rabbit using the Synthesized peptide derived from internal of Human CCHL. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
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Western blot analysis of extracts from COS7 cells, using Cytochrome c-type Heme Lyase antibody.
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue using Cytochrome c-type Heme Lyase antibody.2
Immunofluorescence analysis of MCF-7 cells, using Cytochrome c-type Heme Lyase antibody.3
| Cat.No | ADC-41696A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HCCS |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human CCHL. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P53701 |
Uniprot Id
P53701
Target Species
Human
Target Name
HCCS
Target Full Name
Holocytochrome c-type synthase
Target Function
Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
Target Involvement
Linear skin defects with multiple congenital anomalies 1 (LSDMCA1)
Target Subcellular Location
Mitochondrion inner membrane. Membrane; Lipid-anchor.
Target Protein Families
Cytochrome c-type heme lyase family
Target Research Area
Cardiovascular
Target Synonyms
CCHL; CCHL_HUMAN; cytochrome c heme-lyase; Cytochrome c-type heme lyase; DKFZp779I1858; EC 4.4.1.17; Hccs; Holocytochrome c synthase (cytochrome c heme lyase) ; Holocytochrome c synthase; Holocytochrome c type synthase ; Holocytochrome c-type synthase; MCOPS7 ; OTTHUMP00000022903; OTTHUMP00000022904; OTTHUMP00000022905; OTTMUSP00000021173; OTTMUSP00000021174; RGD1563855; RP23-37L2.1
Target Background
The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.
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