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Rabbit anti-Human SPIC Polyclonal Antibody

The antibody against SPIC was raised in rabbit using the Synthesized peptide derived from internal of Human SPIC. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-41890A

The antibody against SPIC was raised in rabbit using the Synthesized peptide derived from internal of Human SPIC. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-41890A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSPIC
FormLiquidSpecies ReactivityHuman
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from internal of Human SPIC.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8N5J4
Background Information
  • Uniprot Id

    Q8N5J4

  • Target Species

    Human

  • Target Name

    SPIC

  • Target Full Name

    Transcription factor Spi-C

  • Target Function

    Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    ETS family

  • Target Tissue Specificity

    Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.

  • Target Synonyms

    AU019198; C76795; MGC40611; MGC80555; Prf; Pu.1 related factor; Spi C; Spi C transcription factor; Spi-C transcription factor (Spi-1/PU.1 related); spiC; SPIC_HUMAN; Transcription factor Spi-C

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