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The antibody against Tp53inp2 was raised in rabbit using the Synthesized peptide derived from internal of Human TP53INP2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC, IF.
The antibody against Tp53inp2 was raised in rabbit using the Synthesized peptide derived from internal of Human TP53INP2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC, IF.
$297.00
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TP53INP2 antibody.
Immunofluorescence analysis of MCF-7 cells, using TP53INP2 antibody.2
| Cat.No | ADC-41895A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TP53INP2 |
| Target Synonyms | Tp53inp2 antibody; Dor antibody; Trp53inp2 antibody; Tumor protein p53-inducible nuclear protein 2 antibody; Diabetes and obesity-regulated protein antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human TP53INP2. | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8CFU8 |
Uniprot Id
Q8CFU8
Target Species
Mouse
Target Name
TP53INP2
Target Full Name
Tumor protein p53-inducible nuclear protein 2
Target Function
Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.
Target Subcellular Location
Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome.
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