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The antibody against SRY was raised in rabbit using the Synthesized peptide derived from internal of Human SRY. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against SRY was raised in rabbit using the Synthesized peptide derived from internal of Human SRY. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from HeLa cells, using SRY antibody.
| Cat.No | ADC-41987A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRY |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human SRY. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q05066 |
Uniprot Id
Q05066
Target Species
Human
Target Name
SRY
Target Full Name
Sex-determining region Y protein
Target Function
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons.
Target Involvement
46,XY sex reversal 1 (SRXY1); 46,XX sex reversal 1 (SRXX1)
Target Subcellular Location
Nucleus speckle. Cytoplasm. Nucleus.
Target Protein Families
SRY family
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