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Rabbit anti-Human LILRA3 Polyclonal Antibody

The antibody against LILRA3 was raised in rabbit using the Recombinant Human Leukocyte immunoglobulin-like receptor subfamily A member 3 protein (222-313AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

ADC-05573A

The antibody against LILRA3 was raised in rabbit using the Recombinant Human Leukocyte immunoglobulin-like receptor subfamily A member 3 protein (222-313AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-05573A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLILRA3
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Leukocyte immunoglobulin-like receptor subfamily A member 3 protein (222-313AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8N6C8
Background Information
  • Uniprot Id

    Q8N6C8

  • Target Species

    Human

  • Target Name

    LILRA3

  • Target Full Name

    Leukocyte immunoglobulin-like receptor subfamily A member 3

  • Target Function

    Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.

  • Target Subcellular Location

    Secreted.

  • Target Tissue Specificity

    Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung.

  • Target Synonyms

    CD 85E; CD85 antigen-like family member E; CD85e; CD85e antigen; e3; HM 31; HM 43; HM31; HM43; ILT 6; ILT-6; ILT6; Immunoglobulin like transcript 6; Immunoglobulin-like transcript 6; Leucocyte immunoglobulin like receptor; Leukocyte immunoglobulin like receptor 4; Leukocyte immunoglobulin like receptor A3; Leukocyte immunoglobulin like receptor subfamily A (without TM domain) member 3; Leukocyte immunoglobulin like receptor subfamily A member 3; Leukocyte immunoglobulin-like receptor 4; Leukocyte immunoglobulin-like receptor subfamily A member 3; LILRA 3; LILRA3; LIR 4; LIR-4; LIR4; LIRA3_HUMAN; Monocyte inhibitory receptor HM43/HM31

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