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The antibody against SHPRH was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase SHPRH protein (1362-1512AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SHPRH was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase SHPRH protein (1362-1512AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-05726A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SHPRH |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human E3 ubiquitin-protein ligase SHPRH protein (1362-1512AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q149N8 |
Uniprot Id
Q149N8
Target Species
Human
Target Name
SHPRH
Target Full Name
E3 ubiquitin-protein ligase SHPRH
Target Function
E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'.
Target Protein Families
SNF2/RAD54 helicase family
Target Tissue Specificity
Broadly expressed.
Target Synonyms
bA545I5.2; E3 ubiquitin-protein ligase SHPRH; FLJ27258; FLJ37625; FLJ45012; FLJ90837; histone-linker; KIAA2023; MGC134886; PHD and RING finger domain-containing helicase; Shprh; SHPRH_HUMAN; SNF2; SNF2 histone linker PHD RING helicase
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