Rabbit anti-Human ACBD3 Polyclonal Antibody

Uniprot Id

Q9H3P7

Target Species

Human

Target Name

ACBD3

Target Full Name

Golgi resident protein GCP60

Target Function

Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells. Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase.; (Microbial infection) Plays an essential role in Aichi virus RNA replication by recruiting PI4KB at the viral replication sites.

Target Subcellular Location

Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion.

Target Tissue Specificity

Ubiquitous, with highest expression in testis and ovary.

Target Synonyms

ACBD 3; ACBD3; Acyl CoA binding domain containing protein 3; Acyl Coenzyme A binding domain containing 3; Acyl-CoA-binding domain-containing protein 3; GCP 60; GCP60; GCP60_HUMAN; GOCAP 1; GOCAP1; Golgi complex associated protein 1 60kDa; Golgi complex associated protein 1; Golgi complex-associated protein 1; Golgi phosphoprotein 1; Golgi resident protein GCP60; GOLPH 1; GOLPH1; PAP 7; PAP7; PBR and PKA associated protein 7; PBR associated protein; PBR- and PKA-associated protein 7; Peripheral benzodiazepine receptor associated protein PAP7; Peripheral benzodiazepine receptor-associated protein PAP7; Peripherial benzodiazepine receptor associated protein; PKA (RIalpha) associated protein

Target Background

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation.