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The antibody against CTDNEP1 was raised in rabbit using the Recombinant Human CTD nuclear envelope phosphatase 1 protein (3-244AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CTDNEP1 was raised in rabbit using the Recombinant Human CTD nuclear envelope phosphatase 1 protein (3-244AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human testis tissue using CTDNEP1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human gastric cancer using CTDNEP1 Antibody at dilution of 1:1002
| Cat.No | ADC-50412A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CTDNEP1 |
| Target Synonyms | CTDNEP1; DULLARD; CTD nuclear envelope phosphatase 1; Serine/threonine-protein phosphatase dullard | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human CTD nuclear envelope phosphatase 1 protein (3-244AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95476 |
Uniprot Id
O95476
Target Species
Human
Target Name
CTDNEP1
Target Full Name
CTD nuclear envelope phosphatase 1
Target Function
Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Target Protein Families
Dullard family
Target Tissue Specificity
Muscle specific with lower expression in other metabolic tissues.
Target Synonyms
CTDNEP1; DULLARD; CTD nuclear envelope phosphatase 1; Serine/threonine-protein phosphatase dullard
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