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The antibody against MT-ND2 was raised in rabbit using the Human ND2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against MT-ND2 was raised in rabbit using the Human ND2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-51200A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MT-ND2 |
| Target Synonyms | MT-ND2 antibody; MTND2 antibody; NADH2 antibody; ND2 antibody; NADH-ubiquinone oxidoreductase chain 2 antibody; EC 7.1.1.2 antibody; NADH dehydrogenase subunit 2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human ND2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P03891 |
Uniprot Id
P03891
Target Species
Human
Target Name
MT-ND2
Target Full Name
NADH-ubiquinone oxidoreductase chain 2
Target Function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Target Involvement
Leber hereditary optic neuropathy (LHON); Alzheimer disease mitochondrial (AD-MT)
Target Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Target Protein Families
Complex I subunit 2 family
Target Synonyms
MT-ND2; MTND2; NADH2; ND2; NADH-ubiquinone oxidoreductase chain 2; EC 7.1.1.2; NADH dehydrogenase subunit 2
Target Background
Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Part of mitochondrial respiratory chain complex I. Implicated in Leber hereditary optic neuropathy; multiple sclerosis; myocardial infarction; neurodegenerative disease (multiple); and urinary bladder cancer.
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