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The antibody against TIMM44 was raised in rabbit using the Human TIMM44 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
The antibody against TIMM44 was raised in rabbit using the Human TIMM44 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
$600.00
| Cat.No | ADC-51589A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TIMM44 |
| Target Synonyms | TIMM44 antibody; MIMT44 antibody; TIM44 antibody; Mitochondrial import inner membrane translocase subunit TIM44 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Human TIMM44 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43615 |
Uniprot Id
O43615
Target Species
Human
Target Name
TIMM44
Target Full Name
Mitochondrial import inner membrane translocase subunit TIM44
Target Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.
Target Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Mitochondrion matrix.
Target Protein Families
Tim44 family
Target Synonyms
TIMM44; MIMT44; TIM44; Mitochondrial import inner membrane translocase subunit TIM44
Target Background
This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma.
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